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Impact of systemic SARS-CoV-2 vaccination on mucosal IgA responses to subsequent breakthrough infection.
Marking U. eBioMedicine 2025;:https://doi.org/10.1016/j.ebiom.2025.105912.
[The observation that repeated mucosal exposures elicit enhanced and long-lasting mucosal IgA responses strengthens the rationale for developing mucosal vaccines. While systemic vaccination remains essential for preventing severe disease, findings suggest that it may influence subsequent generation of mucosal IgA trough a reduction of viral load and inflammation in the mucosa.]
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Age Groups
Adults
Conditions and Lifestyle Factors
Coronavirus Infections
Settings
Population Health
Staff Groups
Immunisation