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Common and rare variant analyses reveal genetic factors underlying idiopathic pulmonary fibrosis and its shared aetiology with severe COVID-19.
Kousathanas A. eBioMedicine 2025;:https://doi.org/10.1016/j.ebiom.2025.106048.
[Genetic association studies for idiopathic pulmonary fibrosis have identified several associations and probable effector genes that could not only help understanding IPF pathogenesis but also develop effective treatments. These findings prioritise probable effector genes mediating IPF risk and identify potential therapeutic targets that require validation, with genes colocalising with severe COVID-19 suggesting potential for developing common treatments.]
Freely available online
Age Groups
Adults
Conditions and Lifestyle Factors
Coronavirus Infections
Pulmonary Fibrosis
Settings
Hospital Laboratories
Staff Groups
Biomedical Scientist
Clinical Scientist