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Published

Elevated SARS-CoV-2 IgG4 in plasma and mucosa following repeated mRNA boosters impact antibody functions to Omicron and sarbecoviruses.
Selva KJ. eBioMedicine 2026;:https://doi.org/10.1016/j.ebiom.2025.106087.
[Repeated COVID-19 mRNA boosters improved neutralising and non-neutralising activity across viral variants for both cohorts, though these responses were dampened by increasing IgG4 antibodies. This work emphasises the potential longitudinal effects of booster-induced IgG4 subclass switching.]
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