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SARS-CoV-2 infectious shedding and rebound among adults with and without oral antiviral use: two case-ascertained prospective household studies.
Shah MM. The Lancet Microbe 2026;:https://doi.org/10.1016/j.lanmic.2025.101227.
[COVID-19 oral antiviral treatment was associated with earlier cessation of infectious viral shedding in the absence of viral RNA rebound. However, treatment with antivirals was also associated with a brief rebound in SARS-CoV-2. Communication of these transmission risks and benefits could help eligible patients at high risk of severe COVID-19 and clinicians make informed decisions surrounding oral antiviral use.]
Freely available online
Age Groups
Adults
Conditions and Lifestyle Factors
Coronavirus Infections
Settings
General Practice
Hospital Ward
Intensive Care
Staff Groups
Drug Therapy