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Elevated body mass index is associated with delayed protective airway mucosal immune responses in mild SARS-CoV-2 infection.
Fenn J. eBioMedicine 2026;:https://doi.org/10.1016/j.ebiom.2026.106215.
[SARS-CoV-2 viral load in the upper respiratory tract (URT) typically peaks and declines within days of infection, even in individuals without prior infection or vaccination. Elevated BMI retards initial airway mucosal innate immune responses to infection, which may partially explain the pronounced adverse impact of higher BMI on clinical and virological outcomes in COVID-19.]
Freely available online
Age Groups
Adults
Conditions and Lifestyle Factors
Coronavirus Infections
Obesity
Settings
Hospital Ward
Intensive Care
Staff Groups
Medic